Impairments in activities of daily living (ADL) are a criterion for Alzheimer’s disease (AD) dementia. However, ADL gradually decline in AD, impacting on advanced (a-ADL, complex interpersonal or social functioning), instrumental (IADL, maintaining life in community), and finally basic functions (BADL, activities related to physiological and self-maintenance needs). Information and communication technologies (ICT) have become an increasingly important aspect of daily functioning. Yet, the links of ADL, ICT, and neuropathology of AD dementia are poorly understood. Such knowledge is critical as it can provide biomarker evidence of functional decline in AD.
Hesse E, Mikulan E, Sitt JD, Garcia MDC, Silva W, Ciraolo C, Vaucheret E, Raimondo F, Baglivo F, Adolfi F, Herrera E, Bekinschtein TA, Petroni A, Lew S, Sedeno L, Garcia AM, Ibanez A. Consistent gradient of performance and decoding of stimulus type and valence from local and network activity.
